The timely development of vaccines to emergent diseases require research tools and reference materials. Our specialist containment facilities and experienced staff, enables us to respond when a novel disease emerges.
Within the NIBSC, the Division of Infectious Disease Diagnostics works closely with the Division of Virology and external organisations such as Dstl and PHE to develop models that are applied in support of the establishment of appropriate standards and reference materials for vaccines.These models are used to:
This work has attracted significant external grant funding from Innovate UK and UKRI.
High susceptibility, viral dynamics and persistence of South American Zika virus in New World monkey species. Sci Rep. 2019; 9: 14495.
Towards quantification of protective antibody responses by passive transfer of the 1st WHO International Standard for Ebola virus antibody in a guinea pig model. Vaccine. 2020 Jan 10;38(2):345-349.
Antibody-mediated protection against MERS-CoV in the murine model. Vaccine. 2019 Jul 9;37(30):4094-4102.
Utility of reference materials for Zika Virus nucleic acid testing. Biologicals. 2019 Sep; 61:55-60.
Neil Almond, Head of Infectious Disease DiagnosticsNeil Berry, Principal ScientistDeborah Ferguson, Principal Scientist