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Product details

ID1161
TitleLAI-M184V (3TC-resistant)
CharacteristicsProduced by electroporation of MT-2 cells with HIV-1 LAI proviral DNA encoding the M184V RT substitution. Highly cytopathic; replicates to high titers (>105 TCID50/ml). The virus is highly resistant to 3TC, with IC50 values >60 µM in HeLa-CD4/LacZ-1 cell
SourceDr. John Mellors and Dr. Raymond Schinazi.
ReferenceSchinazi RF. Antimicrob Agents Chemother 37:875-881, 1993.
 
 
 
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